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The effects of COVID-19 pandemic on patients with narcolepsy. 62 of 450 Concerts & Shows in New York City. Rodrigues Aguilar AC, Frange C, Huebra L, Dias Gomes AC, Tufik S, Morgadinho Santos Coelho F. Reinforcing the importance of daily routines and exposure to sunlight for patients with narcolepsy may help to alleviate this observed change. The altered bedtime schedules were associated with an increase in excessive daytime sleepiness, which may in turn explain the increase in the use of stimulants. The results of this study showed that the coronavirus pandemic has significantly impacted the sleep of individuals with narcolepsy. Future research including these observations is warranted. Limitations to this study include the lack of a sleep diary and the failure to capture some narcolepsy symptoms and quality of life data.
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An increase in the use of stimulants by patients using monotherapy and a decrease in the use of antidepressants, stimulants associated with antidepressants, or L-carnitine was observed ( P =.014). Changes in bedtime schedules was significantly associated with increased EDS ( P <.01), and a decrease in hallucinations ( P <.01). There was a significant increase in reported excessive daytime sleepiness (EDS) ( P <.01). More patients reported going to be later or had no fixed bedtime during the pandemic ( P <.05) as well as waking up later or had no fixed wake-up time ( P <.01). Excessive daytime sleepiness was evaluated using the Epworth Sleepiness Scale, which scores severity of sleepiness from 0 to 24. No patients were diagnosed with COVID-19, though 14.5% experienced COVID-19-like symptoms. Patients were 36.9 years of age on average, and 68.7% were diagnosed with narcolepsy type 1 (NT1). To evaluate the impact of the COVID-19 pandemic on the sleep schedules, symptoms, and the need for medication of individuals with narcolepsy, questionnaire data from 76 patients (68.4% women) diagnosed with idiopathic hypersomnia were analyzed. Though a recent study showed that COVID-19 quarantining has led to people going to bed later, getting up earlier, and getting lower quality sleep, the impact of the COVID-19 pandemic on patients with narcolepsy has not yet been determined. 55.7 of the twins reported no change in sleep quality, whereas smaller proportions reporting a decrease (32.9) or an increase in sleep. The social isolation and interruption of daily routines resulting from COVID-19 precautions may impact individuals’ exposure to the light-dark cycle that regulates the circadian system, and thereby exacerbate existing narcolepsy symptoms. Among the same-sex twin pairs sample, about half of the participants reported no change in sleep amount (50.1), whereas smaller proportions reporting an increase (29.8) or a decrease in sleep amount (19.3). The impact of the coronavirus-2019 (COVID-19) on people’s daily lives has resulted in altered sleep patterns and an increase in narcolepsy symptoms, according to results of a study published in the Journal of Clinical Sleep Medicine.